KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAR2A
All Species:
30.3
Human Site:
T123
Identified Species:
44.44
UniProt:
P13861
Number Species:
15
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P13861
NP_004148.1
404
45518
T123
P
R
V
I
H
P
K
T
D
E
Q
R
C
R
L
Chimpanzee
Pan troglodytes
XP_001148361
477
52826
T197
S
R
I
I
H
P
K
T
D
D
Q
R
N
R
L
Rhesus Macaque
Macaca mulatta
XP_001089109
461
51060
T181
S
R
I
I
H
P
K
T
D
D
Q
R
N
R
L
Dog
Lupus familis
XP_541890
401
45078
T120
P
R
V
I
H
P
K
T
D
Q
Q
R
C
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P12367
401
45371
T120
P
R
V
V
H
P
K
T
D
E
Q
R
C
R
L
Rat
Rattus norvegicus
P12368
401
45522
D121
R
V
V
H
P
K
T
D
E
Q
R
Y
R
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509189
323
36258
G90
G
E
H
V
I
D
Q
G
D
D
G
D
N
F
Y
Chicken
Gallus gallus
Q5ZM91
382
43332
D122
V
R
K
V
I
P
K
D
Y
K
T
M
A
A
L
Frog
Xenopus laevis
NP_001084637
402
45172
T122
V
K
I
L
F
P
K
T
D
D
Q
R
N
R
L
Zebra Danio
Brachydanio rerio
NP_001070838
397
44672
T120
P
R
V
V
H
P
K
T
D
E
Q
R
C
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P81900
377
42730
S127
K
N
V
L
L
F
R
S
L
E
K
E
Q
M
N
Honey Bee
Apis mellifera
XP_392905
383
43849
S128
K
H
I
L
L
F
R
S
L
D
E
D
Q
M
T
Nematode Worm
Caenorhab. elegans
P30625
366
41449
S115
A
T
R
R
S
L
E
S
A
M
R
K
N
L
L
Sea Urchin
Strong. purpuratus
Q26619
369
41770
A124
K
N
I
L
L
F
R
A
L
D
E
K
Q
M
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P07278
416
47201
P161
N
N
F
D
D
W
T
P
D
H
Y
K
E
K
S
Red Bread Mold
Neurospora crassa
Q01386
385
42138
E134
N
F
L
F
N
H
L
E
D
D
Q
S
A
Q
V
Conservation
Percent
Protein Identity:
100
58.4
61.1
91
N.A.
86.8
86.8
N.A.
58.6
35.1
64.8
71.2
N.A.
48.7
49.7
32.9
52.2
Protein Similarity:
100
68.3
70.7
94.5
N.A.
91.3
92
N.A.
69
52.7
80.6
83.6
N.A.
67.8
69
54.9
69
P-Site Identity:
100
73.3
73.3
93.3
N.A.
93.3
6.6
N.A.
6.6
26.6
53.3
93.3
N.A.
13.3
0
6.6
0
P-Site Similarity:
100
86.6
86.6
100
N.A.
100
26.6
N.A.
26.6
40
80
100
N.A.
40
40
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.2
35.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
55.2
51.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
0
0
0
0
7
7
0
0
0
13
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% C
% Asp:
0
0
0
7
7
7
0
13
63
44
0
13
0
0
0
% D
% Glu:
0
7
0
0
0
0
7
7
7
25
13
7
7
0
0
% E
% Phe:
0
7
7
7
7
19
0
0
0
0
0
0
0
7
0
% F
% Gly:
7
0
0
0
0
0
0
7
0
0
7
0
0
0
0
% G
% His:
0
7
7
7
38
7
0
0
0
7
0
0
0
0
0
% H
% Ile:
0
0
32
25
13
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
7
7
0
0
7
50
0
0
7
7
19
0
7
0
% K
% Leu:
0
0
7
25
19
7
7
0
19
0
0
0
0
13
57
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
7
0
19
0
% M
% Asn:
13
19
0
0
7
0
0
0
0
0
0
0
32
0
7
% N
% Pro:
25
0
0
0
7
50
0
7
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
0
13
50
0
19
7
13
% Q
% Arg:
7
44
7
7
0
0
19
0
0
0
13
44
7
44
0
% R
% Ser:
13
0
0
0
7
0
0
19
0
0
0
7
0
0
7
% S
% Thr:
0
7
0
0
0
0
13
44
0
0
7
0
0
0
7
% T
% Val:
13
7
38
25
0
0
0
0
0
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
7
7
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _